#Morphogenesis Wolpert in 70s? Core idea is simply that cells use positional information to specialize or otherwise develop in [[Cell differentiation]]. > [!important] A given cell moved to a different location will behave differently. [[The positional information model postulates that a cell's development depends, in part, on its position in relationship to other parts of the organism.]] [[Cells determine their position during development by measuring the concentration of chemicals called morphogens.]] In biology, the mechanism of position information isn't really known. The most common model is of chemical gradients, though others have been considered. If chemical gradients are used, there is a natural fit with the [[Reaction-diffusion model of morphogenesis]]. In different terms, positional information models the cell's policy with position as an input. - It what way does it matter how the information is being transferred?